CD28 co‐signaling in the adaptive immune response
نویسندگان
چکیده
منابع مشابه
CD28 Aptamers as Powerful Immune Response Modulators
CD28 is one of the main costimulatory receptors responsible for the proper activation of T lymphocytes. We have isolated two aptamers that bind to the CD28 receptor. As a monomer, one of them interfered with the binding of CD28 to its ligand (B7), precluding the costimulatory signal, whereas the other one was inactive. However, dimerization of any of the anti-CD28 aptamers was sufficient to pro...
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ژورنال
عنوان ژورنال: Self/Nonself
سال: 2010
ISSN: 1938-2030,1938-2049
DOI: 10.4161/self.1.3.12968